enEVALUATION OF ANTIEPILEPTIC ACTIVITY OF CALOTROPIS PROCERA LEAVES BY STRYCHNINE INDUCED TONIC CONVULSION IN MICEResearch ArticleBackground: Ethnobotanical and traditional study reveals that Calotropis procera is used extensively by the tribal people in eczema, leprosy, elephantiasis, rheumatism, epilepsy and diarrhea, jaundice and fever. Aim: The present study is an attempt to explore the antiepileptic activity of different leaf extracts of plant C. procera. Methodology: Various C. procera extracts were prepared using aqueous, ethanol, chloroform and petroleum ether as solvents. The extracts were screened for nontoxic prEpilepsy, strychnine, convulsion, Soxhalation, C. procera.16 of Pharmacy Technology, Salipur, Cuttack-754202, OdishayesCHANDRASEKHARBARIKchandanbarik117@gmail.comPhdInstitute of Pharmacy Technology, Salipur, Cuttack-754202, College of Pharmacy, Rondapalli, Jeypore – 764002, Koraput,