Design and Evaluation of Controlled Release Chitosan Microspheres of Aceclofenac

Affiliation
Naresh Kshirasagar *

Vaagdevi College of Pharmacy, Ramnagar, Hanamkonda.
Srilatha . Malvey

Division of Pharmaceutics, Vaagdevi college of Pharmacy, Warangal-506001.
D . Adukondalu

Division of Pharmaceutics, Vaagdevi college of Pharmacy, Warangal-506001
K . Senthil

Division of Pharmaceutics Ultra College of pharmacy, Madurai- 625002
Abstract

In the present investigation we developed novel controlled drug delivery of well-known NSAID Aceclofenac, which was successfully encapsulated into chitosan microspheres by single emulsion and chemical cross linking technique using glutaraldehyde. Prepared microspheres were subjected to FT-IR, SEM, studies. In the FT-IR spectrum of Aceclofenac (ACF) loaded chitosan microspheres does not shown any interaction between polymer and ACF. The size of microspheres of batch VI was positively influenced b

Keywords

NSAID, Microspheres